Wayne State University



College of Liberal Arts & Sciences
Lumigen Instrument Center
L.I.C. - Optical Spectroscopy Instrumentation
 

Optical Spectroscopy Instrumentation

  Jasco FT/IR-6600 Infrared Spectrometer

  • ATR with diamond crystal (4000 to 400 cm-1).
  • DRIFTs accessory for diffuse reflectance.
  • DLATGS Detector, ceramic light source, Ge/KBr beam splitter.
  • KnowItAll software with select databases available.

 

  Jasco V-570 UV-Vis-NIR Spectrophotometer with INS-470 Integrating Sphere Attachment

  • Obtain the absorption, percent transmittance, or percent reflectance spectrum of a solution in the range 190-2500 nm.
  • Dual-beam for beam intensity fluctuations.
  • The integrating sphere attachment is designed to measure the transmittance and reflectance of a sample that diffuses light rather than absorbs light. Can be used for solids or dispersed particles in solution. With the integrating sphere attachment, can scan from 220 nm-2,000 nm.
  • The Specular Reflection attachment is designed to measure the specular reflectivity of a smooth-surface sample relative to an aluminum-deposited plane mirror. The angle of incidence is 5° and the incident wavelength varies from 200 nm-2,200 nm.

  Jasco FP-6500 Spectrofluorometer

  • Collects emission or excitation spectrum in the range 200 to 750 nm.





Malvern Panalytical Zetasizer Nano ZS

  • Determines particle sizes suspended in solution in the range of 0.3 nm to 10 µm
  • 4 mW 633 nm laser
  • Temperature range of cuvette compartment, 0 to 90 °C
  • Measurement angles 13° and 173°





MicroCal Isothermal Titration Calorimeter

    The MicroCal Isothermal Titration Calorimeter (ITC) has designed to measure heat evolved or absorbed in liquid samples as a result of the mixing of precise amounts of reactants. This is a quantitative technique that can determine changes in enthalpy (ΔH), entropy (ΔS), and Gibbs free energy of a reaction simultaneously. It is often used to study the binding of small molecules such as medicinal compounds to larger macromolecules (proteins, DNA, etc.). Microcalorimeter is controlled via the VPViewer software. The operating temperature range and the working volume of the cells are 2–80 ℃ and 1.4 ml, respectively.





MicroCal Differential Scanning Microcalorimeter

    This is an analytical technique that measures the difference in the amount of heat needed to increase the temperature of the reference and a sample as a function of temperature. Microcal Differential Scanning Calorimeter (DSC) operates in the temperature range of −10 – 130 ℃. It is capable of both up-scanning and down-scanning at user-selectable scan rates. Scan rates for up- and down-scanning fall in the range of 0° to +90°/hr. and 0° to −60/hr., respectively. The sample and reference cells have effective volumes of ⁓0.5 ml and are immune to all acids. This method is often used to evaluate shelf life and the thermal stability of drug or other chemical formulations.

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5101 Cass Ave, Detroit, MI 48202
313-577-7784

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